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bicalutamide

This medicine is used to treat advanced prostatic cancer in combination with hormone-associated therapy or surgical castration. It is also used as immediate therapy in localized prostate cancer in patients not being treated with radical prostatectomy (surgical removal of the prostate and some surrounding structures) or radiotherapy (X-rays or similar forms of radiation), and in locally advanced prostate cancer either alone or as an adjunct with radical prostatectomy or radiotherapy. It is also used in treating locally advanced and non-metastatic (cancer that does not spread) prostate cancer when surgical castration or other medical intervention is not possible.

Contradications

The patients with allergies to any of the medicine’s components, and severe hepatic (liver) or renal (kidney) impairment should avoid use of this medicine. Please consult your doctor for further information regarding contraindications.

Side effects

The patients administered with this medicine may experience hot flushes, pruritus (severe skin itching), breast tenderness, nausea, gynecomastia (male breast enlargement), asthenia (weakness), liver function changes (temporary), diarrhea, chest pain (rare), heart failure and other heart function disturbances, weight changes, abdominal pain, dyspepsia (indigestion), depression, alopecia (abnormal hair loss), hair regrowth, hematuria (blood in urine), decreased libido, dizziness, gastrointestinal disturbances, swelling, skin reactions, erectile dysfunction, and sun-exposure sensitivity.

Expert Advice

  • Please contact your doctor if you notice yellowing of your eye or skin.
  • Please contact your doctor if you notice any unusual symptoms such as excessive bleeding or bruising, urine or stool color changes, sleep-pattern changes, urination problems/changes, muscle pain, etc.
  • If you are a diabetic, please regularly monitor blood glucose levels during use of this medicine.

FAQs

1. How do you feel when taking bicalutamide?

You may experience abdominal discomfort, weight changes, depression, breathing difficulty, etc. Please contact your doctor in case of any severe adverse reaction.

2. Is Bicalutamide a form of chemotherapy?

Bicalutamide is a hormone-based chemotherapy agent. It competitively binds to cytosolic androgen receptors in target tissues, and inhibits androgen-receptor binding.

3. How effective is Bicalutamide?

The administration of 150 mg of bicalutamide daily is mostly as effective as surgical removal in patients with locally advanced non-metastatic prostate cancer.

4. Does bicalutamide affect the immune system?

It is not reported to affect the immune system. However, it can cause liver damage and sensitivity to the sun.

5. What happens when I stop taking bicalutamide?

Impotence (loss of sexual ability) may occur. However, it is most likely to return to normal when you discontinue bicalutamide. Breast swelling or tenderness may occur, especially when bicalutamide is used alone.

Medicines containing bicalutamide

Calutide 50mg

By A.J Mirza

Pack size: 10

Rs.1436

Casodex 50mg

By ICI Pakistan Limited

Pack size: 28

Rs.10521.87