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This medicine is used to treat advanced prostatic cancer in combination with hormone-associated therapy or surgical castration. It is also used as immediate therapy in localized prostate cancer in patients not being treated with radical prostatectomy (surgical removal of the prostate and some surrounding structures) or radiotherapy (X-rays or similar forms of radiation), and in locally advanced prostate cancer either alone or as an adjunct with radical prostatectomy or radiotherapy. It is also used in treating locally advanced and non-metastatic (cancer that does not spread) prostate cancer when surgical castration or other medical intervention is not possible.
The patients administered with this medicine may experience hot flushes, pruritus (severe skin itching), breast tenderness, nausea, gynecomastia (male breast enlargement), asthenia (weakness), liver function changes (temporary), diarrhea, chest pain (rare), heart failure and other heart function disturbances, weight changes, abdominal pain, dyspepsia (indigestion), depression, alopecia (abnormal hair loss), hair regrowth, hematuria (blood in urine), decreased libido, dizziness, gastrointestinal disturbances, swelling, skin reactions, erectile dysfunction, and sun-exposure sensitivity.
Pregnancy
The effects of this medicine are unknown in pregnant females. Therefore, please consult your doctor before use.
Lactation
The effects of this medicine are unknown in lactating females. Therefore, please consult your doctor before use.
Precautions
The patients with moderate to severe hepatic (liver) and renal (kidney) impairment and heart function abnormalities and diseases should use this medicine cautiously. Please perform periodic liver function tests and avoid exposure to sunlight and ultraviolet light during use of this medicine. Additionally, please consider withdrawing this medicine if disease progresses and there is Prostatic Serum Antigen elevation (usually indicative of prostatic abnormalities).
The patients with allergies to any of the medicine’s components, and severe hepatic (liver) or renal (kidney) impairment should avoid use of this medicine. Please consult your doctor for further information regarding contraindications.
1. How do you feel when taking bicalutamide?
You may experience abdominal discomfort, weight changes, depression, breathing difficulty, etc. Please contact your doctor in case of any severe adverse reaction.
2. Is Bicalutamide a form of chemotherapy?
Bicalutamide is a hormone-based chemotherapy agent. It competitively binds to cytosolic androgen receptors in target tissues, and inhibits androgen-receptor binding.
3. How effective is Bicalutamide?
The administration of 150 mg of bicalutamide daily is mostly as effective as surgical removal in patients with locally advanced non-metastatic prostate cancer.
4. Does bicalutamide affect the immune system?
It is not reported to affect the immune system. However, it can cause liver damage and sensitivity to the sun.
5. What happens when I stop taking bicalutamide?
Impotence (loss of sexual ability) may occur. However, it is most likely to return to normal when you discontinue bicalutamide. Breast swelling or tenderness may occur, especially when bicalutamide is used alone.
Disclaimer
Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.
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