Denile Plus 40mg/12.5mg tablet

Introduction

Expert Advice

INDICATIONS

This medication is used in the treatment of hypertension (increased blood pressure) as well as cardiovascular (heart and blood vessels) related events in patients with established atherosclerotic (hardening of blood vessels ) cardiovascular( heart and blood vessels ) disease. It is also used in patients with type 2 diabetes. With end organ damage.

CONTRAINDICATIONS

This medication is not recommended in patients with severe hepatic (liver) impairment and various other disorders of the gallbladder.  It is also contraindicated in patients with hypercalcemia (high blood calcium ) and refractory hypokalemia (low blood potassium). For further details , consult your healthcare provider.

PRECAUTIONS

This medication should be used with extreme caution in patients with impaired hepatic (liver) function, and bilateral renal artery stenosis (narrowing of arteries supplying the kidneys).  Mild to moderate renal(kidney ) impairment.  It may also impair glucose tolerance . Patients with renovascular (blood vessels of the kidney) hypertension (high blood pressure) as well as elderly patients should be cautioned against the use of this medication.

SIDE EFFECTS

The patients administered with this medicine may experience respiratory tract infections, back pain, sinusitis (sinus infection), diarrhea, flu-like-symptoms, pharyngitis (inflammation of pharynx), weakness, fever, hyperkalemia (increased potassium levels), hypotension (low blood pressure), renal (kidney) failure, glaucoma (increased pressure in eye), and heart problems.

PREGNANCY

This medication should not be used in pregnancy.

LACTATION

This medication should not be used by lactating mothers.

Primary Uses

Indications

This medication is used in the treatment of hypertension (increased blood pressure) as well as cardiovascular (heart and blood vessels) related events in patients with established atherosclerotic (hardening of blood vessels ) cardiovascular( heart and blood vessels ) disease. It is also used in patients with type 2 diabetes. With end organ damage.

Side Effects

Patients using this medication may at times experience upper respiratory tract infections, back pain, and sinusitis. If you experience any of these symptoms for a prolonged period of time, please consult your doctor.

Contraindications

This medication is not recommended in patients with severe hepatic (liver) impairment and various other disorders of the gallbladder.  It is also contraindicated in patients with hypercalcemia (high blood calcium ) and refractory hypokalemia (low blood potassium). For further details , consult your healthcare provider.

FAQS

Indications:

This medication is used for treating hypertension (high blood pressure), cardiovascular (involving the heart and its blood vessels) events in patients with atherosclerotic disease (plaque build-up inside arteries), and type 2 diabetes mellitus (disease characterized by glucose impairment) with specific organ damage.

Storage:

Please store this medicine at room temperature (18-25 Celsius). Keep medicine away from children, and excessive light and moisture. Read the leaflet provided with the medicine for further storage guidance.

Effects on pregnancy and lactation:

This medicine is not recommended for pregnant females. This medicine is not recommended for nursing females.

Side Effects:

The patients administered with this medicine may experience respiratory tract infections, back pain, sinusitis (sinus infection), diarrhea, flu-like-symptoms, pharyngitis (inflammation of pharynx), weakness, fever, hyperkalemia (increased potassium levels), hypotension (low blood pressure), renal (kidney) failure, glaucoma (increased pressure in eye), and heart problems.

Precautions:

The patients with impaired hepatic (liver) and renal (kidney) function, heart abnormalities, electrolyte disturbances, dietary salt restriction, primary aldosteronism (increase in aldosterone levels), and elderly should use this medicine cautiously.

Administration:

This medicine is mostly taken orally. The dosage is dependent on the severity of condition and response to treatment. Please consult your doctor before use.

Contraindications:

The patients with hepatic (liver) disorders and impairment e.g. cholestasis (reduction or stoppage of bile flow), refractory hypokalemia (decreased potassium levels), and hypercalcemia (increased calcium levels) should avoid use of this medicine.

What are the most common side effects of hydrochlorothiazide?

The more common side effects that can occur with hydrochlorothiazide include blood pressure that is lower than normal (especially when standing up after sitting or lying down), dizziness (feeling like sleeping), headache, and weakness.

What is the best time of day to take hydrochlorothiazide?

If you are to take a single dose a day, take it in the morning after breakfast. If you are to take more than one dose a day, take the last dose no later than 6 p.m., unless otherwise directed by your doctor.

Does hydrochlorothiazide make you pee a lot?

Hydrochlorothiazide belongs to a class of medicine known as diuretics water pills. It works by causing you to make more urine. This helps your body get rid of extra salt and water. This medicine also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease.

How to administer this medicine?

This medicine is mostly used orally. The dose is dependent on the age, condition and its severity.

Can I drink any alcohol at all while taking hydrochlorothiazide?

Drinking alcohol with this medicine can cause side effects.

How to store this medicine?

Please store this medicine at room temperature away from excessive light, moisture, and children.

How long does it take for hydrochlorothiazide to start working?

Pharmacological effects begin in about 2 hours after an oral dose, peaks in 4 hours, and lasts for about 6 to 12 hours.