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rho-d-immune-globulin

This medicine is used in prophylaxis (treatment given to prevent disease) of rhesus sensitization. Rh negative women should receive anti Rh injection at the earliest possible time after delivery of a Rh positive child and after expulsion of placenta (provides oxygen and nutrients to growing baby). Intravenous application should be administered not later than 48 hours after delivery and intramuscular application not later than 72 hours after delivery.

Contradications

This medicine is not approved to be used in the treatment of idiopathic (unknown origin) thrombocytopenic (low levels of platelets) purpura (small blood vessels burst resulting in accumulation of blood under skin) in rhesus negative or splenectomized (partial or complete removal of spleen) patients.

Side effects

Patients administered with this medicine may experience nausea (feeling like vomiting), diarrhea (frequent watery stools), chills, fever, headache, dizziness (feeling like sleeping), arthralgia (joint pain), myalgia (muscle pain), muscle spasm (contraction), lower back pain, allergic reactions, injection site reactions, thromboembolic events (formation of a clot), hypotension (low blood pressure), and acute (short term) renal (kidney) failure.

Expert Advice

  • Before using look out for particles or discoloration.
  • Keep this medicine away from children.
  • Keep this medicine away from direct sunlight.

FAQs

What is rhophylac injection?

Rhophylac is a sterile solution of anti-D, also known as Rho(D) Immune Globulin or Rh factor, which protects against Rh-sensitization.

How do you give rhophylac?

Rhophylac should be administered by intravenous or intramuscular injection. If large doses (greater than 5 mL) are required and intramuscular injection is chosen, it is advisable to administer rhophylac in divided doses at different sites.

How long do anti (D) injections last?

One injection of anti-D immunoglobulin will cover the woman for about 3 months.

Why do I need anti (D) injection?

Rhesus disease can largely be prevented by having an injection of a medicine called anti-D immunoglobulin. This can help to avoid a process known as sensitization, which is when a woman with Rh (D) negative blood is exposed to Rh (D) positive blood and develops an immune response to it.

Is anti (D) injection painful?

Side effects of this medicine are minor, which may include pain at the site of the injection, rash (change in color and texture of skin), and itching.

Medicines containing rho-d-immune-globulin

Rho Gam UF Plus 300mcg

By Amson

Pack size: 1 Pre Filled Syringe

Rs.9000