What is this test?
This laboratory test is performed on a blood sample to evaluate the time required by the blood to clot when certain reagents are added. It finds out the abnormalities in blood clotting and bleeding. It is also used to check if the blood-thinners are working fine.
Why is this test performed?
This test is performed:
- To check the functioning of clotting factors
- To diagnose bleeding or clotting disorders
- To monitor the efficacy of blood-thinners. Such as Heparin
- Before surgical procedures to rule out the risk of uncontrolled bleeding
- To investigate recurrent miscarriages.
- Overview:
-
What is this test?
This laboratory test is performed on a blood sample to evaluate the time required by the blood to clot when certain reagents are added. It finds out the abnormalities in blood clotting and bleeding. It is also used to check if the blood-thinners are working fine.
Why is this test performed?
This test is performed:
- To check the functioning of clotting factors
- To diagnose bleeding or clotting disorders
- To monitor the efficacy of blood-thinners. Such as Heparin
- Before surgical procedures to rule out the risk of uncontrolled bleeding
- To investigate recurrent miscarriages.
- Which coagulation factors does this test cover?
APTT measures the functioning of Coagulation factor I, II, V, XII, VIII, IX, X, and XI. It also measures PK and HK.
- How to prepare for this test?
Avoid a high-fat meal before the collection of blood. No other preparations are required.
- What are the symptoms of a bleeding disorder?
Following are the symptoms of a bleeding disorder:
- Unexplained bleeding
- Bruising
- Unexplained nose bleeding
- Heavy menstrual bleeding.
- What are the risks of this test?
Risks involved in blood withdrawal are rare but include:
- Pain
- Infection
- Bleeding
- Bruising
- Which medicines affect the aPTT results?
- Antihistamines
- Ascorbic acid
- Chlorpromazine
- Heparin
- Vitamin K supplements
Normal range:
APTT: 30-40 seconds
- Interpretation of test results:
Causes of prolonged aPTT:
- Coagulation factor deficiencies
- Leukemia
- Hemophilia
- Use of Heparin or Warfarin
- DIC (disseminated intravascular coagulation)
- Malabsorption
- Lupus anticoagulants.
Causes of shortened aPTT:
- Early stages of DIC
- Ovarian, pancreatic, or colon cancer.
You should get tested if you experience:
- Multiple miscarriages
- Unexplained bleeding
- Delayed clotting
- Gum-bleeding
- Nose bleeding
- Swelling in joints.
