Combihale (0.5mg+2.5mg/2.5mL) nebulizer solution

Introduction

Expert Advice

Indications:

This medicine is used for the prevention and treatment of shortness of breath in patients with Chronic Obstructive Pulmonary Disease (COPD), chronic bronchitis and mild to moderate asthma.

Administration:

This medicine is used with a nebulizer, a machine which changes the solution form into a gaseous form. This gas/mist is then inhaled. The solution must be colorless. Each treatment session usually takes 5-15 minutes.

Make sure to clean the nebulizer to prevent infections. The dosage of this medicine is dependent on the patient’s age, condition and its severity. Please consult your health care provider before use of this medicine.

Storage:

Please store this medicine at room temperature (20-30 Celsius). Keep medicine away from excessive light, moisture, and children.

Side Effects:

Patients administered with this medication may experience headache, dizziness, throat irritation, cough, dry mouth, and nausea. Patients may also experience constipation, urinary retention (inability to urinate completely), occasional paradoxical bronchospasm (narrowing or spasm of airway), tachycardia (increased heart rate), and arrhythmias (disorder of heart rhythm)

Precautions:

This medicine's use should be closely monitored in conditons like glaucoma (Increased intraoccular eye pressure), prostatic hypertrophy (increased number of prostate gland cells) and bladder outlet obstruction (bladder outflow blockage). Protect eyes from this medicine as it may cause irriation. 

Effects on pregnancy and lactation:

The effects are undetermined; therefore, caution is advised. Please consult your health care provider before use.

Contraindications:

This medication is contraindicated in case of hypersensitivity to the active substance i.e. ipratropium bromide or to atropine. 

Primary Uses

Indications

This medicine is used for the prevention and treatment of shortness of breath in patients with Chronic Obstructive Pulmonary Disease (COPD), chronic bronchitis and mild to moderate asthma.

Side Effects

Patients administered with this medication may experience headache, dizziness, throat irritation, cough, dry mouth, and nausea. Patients may also experience constipation, urinary retention (inability to urinate completely), occasional paradoxical bronchospasm (narrowing or spasm of airway), tachycardia (increased heart rate), and arrhythmias (disorder of heart rhythm)

Contraindications

This medication is contraindicated in case of hypersensitivity to the active substance i.e. ipratropium bromide or to atropine. 

FAQS

Does continuous administration of the medicine result in damage within the mouth?

Patients usually complain about dry mouth, which can be avoided by maintaining good oral hygiene and frequent mouth rinses.

Can we self-administer this medicine?

Although you can, but the initial doses usually result in wheezing, a doctor’s supervision is therefore recommended. But once the body adjusts, you are free to self-administer.

Does this medicine have severe side effects?

Severity in side effects is usually not observed, as only a limited quantity of the medicine absorbs in the blood.

Indications:

This medication is used for controlling and preventing symptoms of lung disorders/obstruction such as wheezing, shortness of breath, and feeling of tightness caused by diseases such as Emphysema, Bronchitis, etc. This medicine does not provide quick relief but can be used along with other medicines to reduce lung disease symptoms. It works by widening the air passages allowing easier gaseous exchange.

Administration:

This medicine is used with a nebulizer, a machine which changes the solution form into a gaseous form. This gas/mist is then inhaled. The solution must be colorless. Each treatment session usually takes 5-15 minutes. Make sure to clean the nebulizer to prevent infections. The dosage of this medicine is dependent on the patient’s age, condition and its severity. Please consult your health care provider before use of this medicine.

Storage:

Please store this medicine at room temperature (20-30 Celsius). Keep medicine away from excessive light, moisture, and children

Side Effects:

You may experience the following: • Headache • Dizziness • Nausea and vomiting • Slow or irregular heart beat • May worsen breathing problem right after use • Constipation • Dry mouth • Fatigue • Allergic reactions such as itching, rash, and swelling

Precautions:

Following are the precautions for use of this medicine: • Do not use or discontinue this medicine if you are allergic to any of the ingredients of this medicine • Kidney disease • Liver disease • Any type of cancer • May make you dizzy so it is advised not to do any tasks that require alertness (e.g. driving) immediately after taking this medicine • Drink plenty of water to prevent dehydration • Vision changes • Difficulty urinating • Glaucoma (increased pressure in the eye)

Effects on pregnancy and lactation:

The effects are undetermined; therefore, caution is advised. Please consult your health care provider before use.

This medicine is contraindicated for people with diabetes, an overactive thyroid gland, ketoacidosis (inability of body to use sugars adequately), high blood pressure, coronary insufficiency (diminished blood flow through arteries of the heart), low supply of oxygen rich blood to the heart, heart rhythm issues, and seizures.