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Description

The H1 histamine receptor is responsible for hypersensitivity and allergic reactions. Hydroxyzine is a inverse agonist of histamine H1-receptors. Hydroxyzine is not a cortical depressant, its sedative properties are at subcortical level of CNS, due to these properties it has anxiolytic effects as well.

CONTRAINDICATIONS:

Its use is contraindicated in patients with chronic liver disease, heart rhythm issues, and asthma patients with a history of previous serious antihistamine-induced adverse effects on the lungs.

 

SIDE-EFFECTS:

Side-effects include drowsiness, headache, dry mouth, fatigue and disturbance in heart rhythm.

 

Key Benefits

Used to treat Pruginous affection, respiratory allergies, digestive, skin and mucus membrane allergies, also use to treat nervous stress.

Directions For Use

. Take oral form with or without meals.
. Avoid taking alcohol and CNS depressants during therapy
. Empty bladder before taking medication
. Take sufficient amount of fluid to maintain hydration.

Safety Information/Precautions

This medicine should be cautiously used in patients with liver and kidney problems. Precautions must be taken in heart patients and people with respiratory issues.

 

Patients may experience impaired judgment and dexterity. Caution must be observed in cases of kidney and liver impairment. Bladder obstructions, inability to empty bladder, glaucoma (eye conditions where optic nerve may be damaged), GI obstruction, decreased GI motility, myasthenia gravis (long-term neuromuscular disease), dementia, hyperthyroidism (excess thyroid hormone in the blood), high blood pressure, Benign Prostatic Hypertrophy (noncancerous increase in the size of the prostate gland), seizure disorders, respiratory disorders, stenosing (blocking) stomach ulcer. Patients are advised to report cardiac symptoms and should be monitored for issues with heart rhythm. Use the lowest effective dosage for the shortest time duration. Elderly patients must observe caution.

Faqs

What are food interactions of hydroxyzine?

  • Avoid alcohol. drug administration with alcohol may increase the CNS adverse effects of hydroxyzine.
  • Avoid grapefruit products. drug administration with grapefruit inhibits hydroxyzine metabolism and can result in elevated serum concentrations.

What can be done in case of overdosing of hydroxyzine?

For hydroxyzine overdose, we can consider the induction of vomiting and the use of gastric lavage. Other treatment can be general symptomatic and supportive care. Hypotension is usually controlled by intravenous fluids and pressors, where as caffeine and sodium benzoate injection can be given to patient to counteract any CNS depressant effects.

Disclaimer

Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.

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